Gallic acid monohydrate

I-Gallic acid yi-phenolic acid okanye i-bioactive compound efumaneka kwizityalo.Ineempawu ze-antioxidant kwaye inokubonelela ngezinye izibonelelo zempilo.
Oosokhemesti bayayazi kwaye basebenzisa i-gallic acid kangangeenkulungwane.Ngaphandle koku, kutsha nje sele iyinto eqhelekileyo kwihlabathi lezempilo.
Eli nqaku lichaza yonke into oyifunayo ukuze ukwazi malunga ne-gallic acid, kubandakanywa iingenelo kunye nokungonakali, kunye nalapho ungayifumana khona.
I-Gallic acid (eyaziwa ngokuba yi-3,4,5-trihydroxybenzoic acid) yi-antioxidant kunye ne-phenolic acid efumaneka kwiimali ezahlukeneyo kwizityalo ezininzi (1).
Ukususela kwinkulungwane ye-12 ukuya kweye-19 yayisetyenziswa njengeyona nto iphambili kwi-inki ye-iron gall, i-inki eqhelekileyo yaseYurophu yokubhala.Namhlanje, iinzuzo zayo zempilo ezinokubakho ziya ziqondwa.
Umzimba wakho uwufumana kukutya okuthile kwezityalo.Nangona eminye imithombo ibonisa ukuba i-gallic acid iyafumaneka njengesongezelelo, ibonakala ithengiswa kwifom esetyenziselwa iinjongo zeekhemikhali.
Qaphela ukuba uphando oluninzi olukhoyo kwi-gallic acid lwenziwe kwiityhubhu zokuvavanya kunye nezilwanyana.Ke, akukho bungqina obaneleyo bokuqinisekisa iingcebiso ezicacileyo zedosi, iziphumo ebezingalindelekanga, ukusetyenziswa ngokugqibeleleyo, kunye neenkxalabo zokhuseleko lomntu kule khompawundi (2).
I-asidi ye-Gallic ifumaneka ngokwemvelo kwizityalo ezininzi, ngakumbi i-oak bark kunye ne-African frankincense.
Abantu abaninzi bakufumanisa kuluncedo ukwazi ukuba kukuphi ukutya okuqhelekileyo okuqulethe le nto.Eminye yemithombo yokutya yegallic acid ibandakanya (3, 4):
I-Gallic acid yi-antioxidant kunye ne-phenolic compound efumaneka kwizityalo ezininzi.Imithombo efanelekileyo iquka ukutya okufana namandongomane, amaqunube kunye nezinye iziqhamo ezinokuba sele zibandakanyiwe ekutyeni kwakho.
Nangona uphando olongezelelweyo lufunekayo ukufumanisa izibonelelo zezempilo ezinokuthi zenzeke kwi-gallic acid, uphando lwangoku lubonisa ukuba lunokuba ne-antibacterial, anti-obesity kunye ne-antioxidant properties ezinokuphucula umhlaza kunye nempilo yengqondo.
I-asidi ye-Gallic inokunceda ukulawula amajoni akho omzimba kwaye isebenze njengendlela yokukhusela yendalo ngokuchasene nosulelo lwe-microbial (5).
Uphononongo luphuhlise unyango lwe-antibacterial oluphuculweyo oluphuculweyo ngokubeka i-gallic acid ekukhanyeni kwe-ultraviolet (UV-C).Ilanga likhupha ukukhanya okungabonakaliyo kweultraviolet, ekudla ngokusetyenziswa njengesibulali-ntsholongwane (6).
Ngenxa yoko, umsebenzi we-antimicrobial ubalulekile.Enyanisweni, ababhali bacebisa ukuba i-gallic acid evezwe kwi-UV-C inamandla okuba yi-antimicrobial agent entsha kwiinkqubo zokutya (6).
Ukongeza, uphononongo lwaselabhoratri lufumanise ukuba igallic acid inokwandisa ubomi beshelufu yeetruffle ezimnyama.Ikwenza oku ngokulwa nesingcoliso sebhaktiriya esibizwa ngokuba yiPseudomonas (7).
Uphando olutsha kunye noludala luye lwabonisa ukuba i-gallic acid inokulwa nezinye iintsholongwane zokutya ezifana neCampylobacter, E. coli, i-Listeria monocytogenes kunye ne-Staphylococcus aureus, kunye neebhaktheriya ezifumaneka emlonyeni obizwa ngokuba yi-Streptococcus mutans bacteria (8, 9, 10).).
Kuphononongo olunye, abaphandi bavavanya umsebenzi ochasene nokutyeba kwe-gallic acid.Ngokukodwa, ikhusela ukuvuvukala kunye noxinzelelo lwe-oxidative, olunokuthi lwenzeke kubantu abatyebileyo (12).
Olunye uphando lubonisa ukuba i-gallic acid inciphisa ukuqokelelwa kwamafutha amaninzi kubantu abatyebe kakhulu ngokuthintela i-lipogenesis.I-Lipogenesis yinkqubo apho iikhompawundi ezifana neswekile zenziwe ngamafutha emzimbeni (12).
Kuphononongo lwangaphambili, abantu abadala baseJapan batyebe ngokugqithisileyo bathatha i-gallic acid-rich yaseTshayina isicatshulwa seti emnyama kwidosi yemihla ngemihla ye-333 mg kwiiveki ze-12.Unyango lunciphise kakhulu umjikelezo wesinqe, isalathisi sobunzima bomzimba, kunye namafutha esisu (13).
Nangona kunjalo, ezinye izifundo zabantu zibonise iziphumo ezixubileyo kwesi sihloko.Olunye uphando oludala kunye nolutsha alufumananga nzuzo, ngelixa abanye bacebisa ukuba i-gallic acid inokuphucula iindlela ezithile ezinxulumene nokukhuluphala kunye nomgangatho wobomi (14,15,16,17).
Ngokubanzi, uphando oluninzi luyafuneka kwiinzuzo ezinokubakho ze-gallic acid ekutyebeni kunye neengxaki ezinxulumene nempilo.
I-Gallic acid yi-antioxidant enamandla.Oku kuthetha ukuba kunceda ukulwa noxinzelelo lwe-oxidative, enokuthi bonakalise iiseli kwaye ikhokelela kwizifo ezahlukahlukeneyo ezingapheliyo (18, 19, 20).
Uphando lucebisa ukuba iipropathi ze-gallic acid ze-antioxidant zinokuba phantsi kweenzuzo zayo zokulwa nomhlaza kunye neziphumo ze-neuroprotective, okuthetha ukukwazi kwayo ukukhusela ubume bobuchopho kunye nokusebenza (11, 21, 22).
Uphononongo lwebhubhoratri lubonise ukuba ngelixa i-mango ye-mango inezixhobo zayo ze-antioxidant kunye ne-anti-cancer, i-gallic acid equlethweyo inomsebenzi ochasayo.Oku kuthetha ukuba i-gallic acid inekhono elilodwa lokuthintela ukukhula kunye nokusasazeka kweeseli zomhlaza (23).
Olunye uphando lwebhubhoratri lubeka uluhlu lwe-gallic acid phezu kwe-gamma-AlOOH nanoparticles, okanye i-aluminium-containing mineral particles ene-antioxidant properties.Oku kwafunyanwa ukwandisa amandla e-antioxidant we-nanoparticles (24).
Olunye uphando lubonisa ukuba i-gallic acid inokuthintela ukwehla komsebenzi wengqondo ngokunciphisa ukuvuvukala kunye nomonakalo we-oxidative.Kwakhona kunokunceda ukukhusela i-stroke (25, 26).
Olunye uphando lwezilwanyana lubonisa ukuba i-gallic acid ingaba nefuthe elikhuselayo kwimemori emva kokulimala kwengqondo.Oku kunokuba ngenxa yemisebenzi yayo ye-antioxidant kunye ne-anti-inflammatory (27).
Iziphumo ze-neuroprotective ze-gallic acid ziye zabonwa kwizifundo zezilwanyana.Olu phononongo lujonge izinto ezithile ekucingelwa ukuba zithintela ukonakala kwengqondo kubantu abanesifo seswekile (28).
Ngaphandle kwezi ziphumo zithembisayo, uphando oluninzi lwabantu luyafuneka ukuze kuqondwe ngcono ukuba iipropathi ze-gallic acid ze-antioxidant zinokuzuza njani kwimpilo yabantu.
Uphando lubonisa ukuba i-gallic acid ine-antioxidant enamandla, i-antibacterial properties kwaye inceda ukulwa nokutyeba.Nangona kunjalo, uphando oluninzi lwenziwa kwiityhubhu zokuvavanya kunye nezilwanyana, ngoko ke izifundo zabantu ziyafuneka.
I-asidi ye-Gallic isetyenziswe ngokufanelekileyo kwimithombo yokutya yendalo, ngokukodwa ukungabikho kwezongezelelo ezivunyiweyo nezifundwe kakuhle kwimarike.
Nangona kunjalo, olunye uphononongo lwezilwanyana oluphelelwe lixesha lugqibe kwelokuba i-oral gallic acid ayinatyhefu kwiidosi ukuya kuthi ga kwi-2.3 grams ngeponti yobunzima bomzimba (5 grams ngekhilogram) (29).
Olunye uphando lwezilwanyana lufumene ukuba i-gallic acid elawulwa kwiigundane kwi-dose ye-0.4 mg ngeponti yobunzima bomzimba (i-0.9 g ngekhilogram) imihla ngemihla ngeentsuku ze-28 ibonise ubungqina betyhefu kwiigundane (30).
Eyona nto iphantsi kakhulu kwi-gallic acid kukunqongophala kwezifundo zabantu kunye nokunqongophala kwezongezelelo kunye neengcebiso zedosi ezifundwe kakuhle kunye nophando.
I-Gallic acid yi-phenolic acid efumaneka kwizityalo, ngakumbi iziqhamo, amantongomane, iwayini kunye neti.Ine-antioxidant, i-antibacterial kunye ne-anti-obesity properties.
Ngenxa yendlela esisiseko, inokuba luncedo ngakumbi kwizifo ezinjengomhlaza kunye nempilo yengqondo.Ikwasetyenziswa njengesongezelelo sokutya ukukhusela izifo ezibangelwa kukutya.
Nangona kunjalo, uphando oluninzi lwe-gallic acid lwenziwe kwiityhubhu zokuvavanya kunye nezilwanyana.Ke ngoko, akucaci ukuba izibonelelo zayo ezichaziweyo ziyasebenza na ebantwini.
Ukongezelela, nangona imithombo ethile ibonisa ukuba i-gallic acid ifumaneka njengesongezelelo, kubonakala ngathi ithengiswa ngokukodwa ngeenjongo zekhemikhali.
Ukuba unomdla kwiinzuzo ezinokubakho ze-gallic acid, gxininisa kwimithombo yokutya yendalo kuze kube yilapho uphando olongezelelweyo lwenziwa kwi-gallic acid supplements.
Zama oku namhlanje: Ukongeza i-gallic acid yendalo kwisidlo sakho, yongeza nje iindidi zamandongomane kunye namaqunube kukutya kwakho kwemihla ngemihla.Unokusela nekomityi yeti eluhlaza kunye nesidlo sakusasa.
Iingcali zethu zihlala zibeke iliso kwimpilo kunye nokuba sempilweni kwaye zihlaziya amanqaku ethu njengoko ulwazi olutsha lufumaneka.
Ii-Antioxidants zibaluleke kakhulu, kodwa abantu abaninzi abazazi ngokwenene ukuba ziyintoni na.Eli nqaku liyichaza yonke into ngokobuntu.
Izongezo zinokuba yindlela esebenzayo yokunyusa ukuthathwa kwezakhamzimba njengoko ukhula.Eli nqaku lidwelisa i-10 ezona zongezelelo zokwaluphala okunempilo…
Ubomi bunokuthatha ubunzima kumanqanaba akho amandla.Ngethamsanqa, ezi 11 iivithamini kunye nezongezo zinokunyusa amanqanaba akho amandla xa uwafuna kakhulu.
Izongezo ze-Antioxidant zithandwa, kodwa ubungqina bubonisa ukuba zineengxaki ezininzi.Eli nqaku licacisa ukuba zeziphi izongezo ze-antioxidant ...
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Ingqiqo inqabile xa kuziwa kwisondlo.Nazi iinyaniso ze-20 zesondlo ekufuneka zicace, kodwa azikho.
Ukutya kunye neempembelelo zokuqina komzimba zikhuthaza abantu ukuba batye izinti zebhotolo njengenxalenye yesicwangciso sokutya esine-carb ephantsi, njengokutya kwe-carnivore.Njengokuba……
Uphononongo olutsha lubonisa ukuba izigulane ezininzi ezinesifo senhliziyo zidla kakhulu i-sodium.Nazi iindlela ezi-5 ezilula zokunciphisa iindleko.