Acide Gallic monohydrate

Acide ya Gallic ni aside ya fenolike cyangwa bioactive compound iboneka mu bimera.Ifite antioxydeant kandi irashobora gutanga izindi nyungu zubuzima.
Abashinzwe imiti bamenye kandi bakoresha aside gallic mu binyejana byinshi.Nubwo bimeze gurtyo, iherutse kuba inzira nyamukuru kwisi yubuzima.
Iyi ngingo isobanura ibintu byose ukeneye kumenya kuri acide gallic, harimo ibyiza byayo nibibi, n'aho wabisanga.
Acide ya Gallic (izwi kandi nka 3,4,5-trihydroxybenzoic aside) ni antioxydeant na aside fenolike iboneka muburyo butandukanye mubihingwa byinshi (1).
Kuva mu kinyejana cya 12 kugeza mu cya 19 byakoreshwaga nk'ibikoresho by'ingenzi muri wino y'icyuma, wino isanzwe yo mu Burayi.Muri iki gihe, inyungu zayo ku buzima ziragenda zimenyekana.
Umubiri wawe ubikura mubiryo bimwe na bimwe byibimera.Nubwo amasoko amwe yerekana ko aside gallic nayo iboneka nkinyongera, bigaragara ko igurishwa muburyo bukoreshwa mubikorwa bya shimi.
Menya ko ubushakashatsi bwinshi buriho kuri acide gallic bwakorewe mubitereko no mubikoko.Kubwibyo, hari ibimenyetso bidahagije byerekana ibyifuzo bisobanutse neza, ingaruka mbi, imikoreshereze myiza, hamwe n’umutekano w’abantu kuri iki kigo (2).
Acide ya Gallic iboneka mubisanzwe mubihingwa byinshi, cyane cyane igishishwa cya oak nububani bwa Afrika.
Abantu benshi basanga ari byiza kumenya ibiryo bisanzwe birimo iyi ngingo.Amwe mumasoko meza yibiribwa bya acide gallic arimo (3, 4):
Acide Gallic ni antioxydeant na fenolike iboneka mu bimera byinshi.Inkomoko nziza zirimo ibiryo nk'imbuto, imbuto n'izindi mbuto zishobora kuba zashyizwe mu ndyo yawe.
Nubwo hakenewe ubushakashatsi bwinshi kugirango hamenyekane ingaruka zubuzima bwa aside gallike, ubushakashatsi bwakozwe burerekana ko bushobora kuba bufite antibacterial, anti-semizite na antioxydeant ishobora guteza kanseri nubuzima bwubwonko.
Acide ya Gallic irashobora gufasha kugenzura imikorere yumubiri wawe kandi ikora nkuburyo bwo kwirinda indwara zanduza mikorobe (5).
Ubushakashatsi bwashyizeho uburyo bushya bwo kongera imiti igabanya ubukana bwa antibacterial mu kwerekana aside gallic ku mucyo ultraviolet (UV-C).Izuba risohora urumuri rutagaragara rwa ultraviolet, rukunze gukoreshwa nk'udukoko twangiza (6).
Nkigisubizo, ibikorwa bya mikorobe ni ngombwa.Mubyukuri, abanditsi bavuga ko aside gallic ihura na UV-C ifite ubushobozi bwo kuba imiti mishya ya mikorobe muri sisitemu y'ibiribwa (6).
Byongeye kandi, ubushakashatsi bwakorewe muri laboratoire bwerekanye ko aside gallic ishobora kongera igihe cyubuzima bwimitsi mishya yumukara.Irabikora mukurwanya indwara ya bagiteri yitwa Pseudomonas (7).
Ubushakashatsi bwakera ndetse bushya bwerekanye ko aside gallic ishobora kurwanya izindi ndwara ziterwa n’ibiribwa nka Campylobacter, E. coli, Listeria monocytogenes na Staphylococcus aureus, ndetse na bagiteri ziboneka mu kanwa bita Streptococcus mutans bacteria (8, 9, 10).).
Mu isuzuma rimwe, abashakashatsi basuzumye ibikorwa byo kurwanya umubyibuho ukabije wa aside gallic.By'umwihariko, irinda umuriro no guhagarika umutima, bishobora kugaragara ku bantu bafite umubyibuho ukabije (12).
Ubushakashatsi bumwe bwerekana ko aside gallic igabanya ibinure byinshi kubantu bafite umubyibuho ukabije babuza lipogenezi.Lipogenezez ni inzira ikomatanya nk'isukari ihindurwamo ibinure mu mubiri (12).
Mu bushakashatsi bwakozwe mbere, abayapani bakuze bafite ibiro byinshi bafashe aside ya gallic ikungahaye ku cyayi cy'umukara ku gipimo cya buri munsi cya mg 333 mu byumweru 12.Ubuvuzi bwagabanutse cyane bivuze kuzenguruka mu kibuno, kwerekana umubiri, hamwe n’ibinure byo munda (13).
Ariko, ubundi bushakashatsi bwabantu bwerekanye ibisubizo bivanze kuriyi ngingo.Ubushakashatsi bumwe na bumwe bushya kandi bushya bwabonye nta nyungu, mu gihe ubundi buvuga ko aside gallic ishobora kunoza uburyo bumwe na bumwe bujyanye n'umubyibuho ukabije ndetse n'ubuzima bwiza (14,15,16,17).
Muri rusange, hakenewe ubushakashatsi bwinshi ku nyungu zishobora guterwa na aside gallike ku mubyibuho ukabije hamwe n’ingaruka ziterwa n’ubuzima.
Acide Gallic ni antioxydants ikomeye.Ibi bivuze ko bifasha kurwanya stress ya okiside, ishobora kwangiza selile kandi igatera indwara zitandukanye zidakira (18, 19, 20).
Ubushakashatsi bwerekana ko antioxydants ya aside ya gallic ishobora gushingira ku nyungu zayo zitwa anticancer n'ingaruka za neuroprotective, bivuze ko ifite ubushobozi bwo kurinda imiterere n'ubwonko (11, 21, 22).
Ubushakashatsi bwakorewe muri laboratoire bwerekanye ko mu gihe igishishwa cy’umwembe gifite antioxydeant na anti-kanseri, aside gallic irimo ifite ibikorwa byo kurwanya indwara.Ibi bivuze ko aside gallic ifite ubushobozi budasanzwe bwo gukumira imikurire ya kanseri (23).
Ubundi bushakashatsi bwakorewe muri laboratoire bwashyize urwego rwa acide gallic hejuru ya nanoparticles ya gamma-AlOOH, cyangwa aluminiyumu irimo imyunyu ngugu ya antioxydeant.Ibi wasangaga byongera ubushobozi bwa antioxydeant ya nanoparticles (24).
Ubushakashatsi bumwe bwerekana ko aside gallic ishobora kwirinda kugabanuka kwimikorere yubwonko kugabanya umuriro no kwangiza okiside.Irashobora kandi gufasha kwirinda indwara yubwonko (25, 26).
Ubushakashatsi bumwe bw’inyamaswa ndetse bugaragaza ko aside gallic ishobora kugira ingaruka zo kwibuka nyuma yo gukomeretsa ubwonko.Ibi birashobora guterwa nibikorwa bya antioxydeant na anti-inflammatory (27).
Ingaruka za neuroprotective ya acide gallic nazo zagaragaye mubushakashatsi bwinyamaswa.Ubu bushakashatsi bwarebye ibintu bimwe na bimwe bibwira ko birinda ubwonko ubwonko ku bantu barwaye diyabete (28).
Nubwo ibyo bisubizo bitanga icyizere, ubushakashatsi bwabantu burakenewe kugirango twumve neza uburyo antioxydants ya aside ya gallic ishobora kugirira akamaro ubuzima bwabantu.
Ubushakashatsi bwerekana ko aside gallic ifite antioxydants ikomeye, antibacterial ndetse ikanafasha kurwanya umubyibuho ukabije.Nyamara, ubushakashatsi bwinshi bukorerwa mumiyoboro yipimisha no ku nyamaswa, bityo ubushakashatsi bwabantu burakenewe.
Acide ya Gallic ikoreshwa neza mubikomoka ku biribwa bisanzwe, cyane cyane bitewe no kubura inyongeramusaruro zemewe kandi zize neza ku isoko.
Nyamara, ubushakashatsi bumwe bw’inyamaswa zashaje bwanzuye ko aside gallic yo mu kanwa idafite uburozi mu kigero cya garama 2,3 kuri kilo y’ibiro by’umubiri (garama 5 ku kilo) (29).
Ubundi bushakashatsi bw’inyamaswa bwerekanye ko aside gallic yahawe imbeba ku kigero cya 0.4 mg ku kilo cy’ibiro by’umubiri (0,9 g ku kilo) buri munsi mu minsi 28 nta kimenyetso cyerekana uburozi bw’imbeba (30).
Ikibi gikomeye kuri acide gallic nukubura ubushakashatsi bwabantu no kubura inyongeramusaruro hamwe nubushakashatsi bwakozwe neza kandi bushyigikiwe nubushakashatsi.
Acide Gallic ni aside ya fenolike iboneka mu bimera, cyane cyane imbuto, imbuto, vino n'icyayi.Ifite antioxydants, antibacterial ndetse niyo ishobora kurwanya umubyibuho ukabije.
Bitewe nuburyo bwibanze, birashobora kugirira akamaro cyane indwara nka kanseri nubuzima bwubwonko.Ikoreshwa kandi nk'inyongera y'ibiryo kugirango wirinde indwara ziterwa n'ibiribwa.
Nyamara, ubushakashatsi bwinshi kuri acide gallic bwakorewe mu tubari no mu nyamaswa.Kubwibyo, ntibisobanutse niba inyungu zayo zitwa ko nazo zireba abantu.
Byongeye kandi, nubwo hari amasoko yerekana ko aside gallic iboneka nkinyongera, bigaragara ko igurishwa cyane cyane mubikorwa bya shimi.
Niba ushishikajwe ninyungu zishobora guterwa na acide gallic, jya wibanda kumasoko y'ibiribwa bisanzwe kugeza igihe ubushakashatsi bwinshi bukozwe kuri aside aside.
Gerageza uyu munsi: Kugirango wongere aside irike ya gallic mumirire yawe, ongeramo gusa imbuto nimbuto zitandukanye mumirire yawe ya buri munsi.Urashobora kandi kunywa igikombe cyicyayi kibisi hamwe na mugitondo.
Inzobere zacu zihora zikurikirana ubuzima nubuzima bwiza no kuvugurura ingingo zacu uko amakuru mashya aboneka.
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