Gallic acid monohydrate

Gallic acid ndi phenolic acid kapena bioactive pawiri yomwe imapezeka muzomera.Lili ndi ma antioxidant ndipo limatha kupereka maubwino ena azaumoyo.
Akatswiri a zamankhwala adziwa ndikugwiritsa ntchito gallic acid kwa zaka zambiri.Ngakhale zili choncho, posachedwapa zakhala zofala kwambiri padziko lonse lapansi.
Nkhaniyi ikufotokoza zonse zomwe muyenera kudziwa zokhudza gallic acid, kuphatikizapo ubwino ndi kuipa kwake, komanso komwe mungapeze.
Gallic acid (yomwe imadziwikanso kuti 3,4,5-trihydroxybenzoic acid) ndi antioxidant ndi phenolic acid yomwe imapezeka mosiyanasiyana muzomera zambiri (1).
Kuyambira m'zaka za m'ma 1200 mpaka 1900 inkiyi inkagwiritsidwa ntchito ngati inki yopangira ndulu yachitsulo, inki yodziwika bwino yaku Europe.Masiku ano, ubwino wake wathanzi ukudziwika kwambiri.
Thupi lanu limachipeza kuchokera ku zakudya zina za zomera.Ngakhale magwero ena akuwonetsa kuti gallic acid imapezekanso ngati chowonjezera, ikuwoneka kuti ikugulitsidwa mu mawonekedwe omwe amagwiritsidwa ntchito pazinthu za mankhwala.
Dziwani kuti kafukufuku wochuluka wa gallic acid wachitika m'machubu oyesera ndi nyama.Chifukwa chake, palibe umboni wokwanira wotsimikizira malingaliro omveka bwino a mlingo, zotsatirapo zake, kugwiritsa ntchito moyenera, komanso nkhawa zachitetezo cha anthu pagululi (2).
Gallic acid imapezeka mwachilengedwe muzomera zambiri, makamaka khungwa la oak ndi lubani waku Africa.
Anthu ambiri amaona kuti n’zothandiza kudziwa kuti ndi zakudya ziti zomwe zili ndi mankhwalawa.Zina mwazakudya zabwino kwambiri za gallic acid ndi (3, 4):
Gallic acid ndi antioxidant ndi phenolic pawiri yomwe imapezeka muzomera zambiri.Magwero abwino amaphatikizapo zakudya monga mtedza, zipatso ndi zipatso zina zomwe zingakhale kale m'zakudya zanu.
Ngakhale kuti kafukufuku wochuluka akufunika kuti adziwe ubwino wa thanzi la gallic acid, kafukufuku wamakono akusonyeza kuti akhoza kukhala ndi antibacterial, anti-obesity ndi antioxidant katundu omwe angapangitse khansa ndi ubongo.
Gallic acid imatha kuwongolera chitetezo chamthupi ndikukhala ngati njira yodzitetezera ku matenda obwera chifukwa cha tizilombo toyambitsa matenda (5).
Kafukufukuyu adapanga njira yatsopano yopangira mankhwala oletsa mabakiteriya owonjezera kuwala powonetsa gallic acid ku kuwala kwa ultraviolet (UV-C).Dzuwa limatulutsa kuwala kosaoneka kwa ultraviolet komwe kumagwiritsidwa ntchito ngati mankhwala ophera tizilombo toyambitsa matenda (6).
Chifukwa chake, ntchito ya antimicrobial ndiyofunikira.M'malo mwake, olembawo akuwonetsa kuti gallic acid yomwe imawululidwa ndi UV-C imatha kukhala antimicrobial wothandizira muzakudya (6).
Kuphatikiza apo, kafukufuku wa labotale adapeza kuti gallic acid imatha kukulitsa moyo wa alumali wa ma truffles akuda atsopano.Imachita izi polimbana ndi kachilombo koyambitsa matenda kotchedwa Pseudomonas (7).
Kafukufuku wakale ndi watsopano wasonyeza kuti gallic acid imatha kulimbana ndi tizilombo toyambitsa matenda monga Campylobacter, E. coli, Listeria monocytogenes ndi Staphylococcus aureus, komanso mabakiteriya omwe amapezeka pakamwa otchedwa Streptococcus mutans bacteria (8, 9, 10).).
Mu ndemanga imodzi, ofufuza adafufuza ntchito yolimbana ndi kunenepa kwambiri ya gallic acid.Makamaka, imateteza ku kutupa ndi kupsinjika kwa okosijeni, komwe kumatha kuchitika mwa anthu onenepa kwambiri (12).
Kafukufuku wina akuwonetsa kuti gallic acid amachepetsa kuchuluka kwa mafuta ochulukirapo mwa anthu onenepa kwambiri poletsa lipogenesis.Lipogenesis ndi njira yomwe zinthu monga shuga zimapangidwira kukhala mafuta m'thupi (12).
Mu kafukufuku wam'mbuyomu, akuluakulu aku Japan onenepa kwambiri adatenga tiyi wakuda wakuda waku China wokhala ndi gallic acid pa mlingo watsiku ndi tsiku wa 333 mg kwa milungu 12.Kuchiza kunachepetsa kwambiri kuchuluka kwa chiuno, kuchuluka kwa thupi, ndi mafuta am'mimba (13).
Komabe, maphunziro ena aumunthu awonetsa zotsatira zosiyana pamutuwu.Maphunziro ena akale ndi atsopano sanapeze phindu, pamene ena amanena kuti gallic acid ikhoza kusintha njira zina zokhudzana ndi kunenepa kwambiri komanso moyo wabwino (14,15,16,17).
Ponseponse, kafukufuku wochulukirapo akufunika pazabwino zomwe zingakhalepo za gallic acid pa kunenepa kwambiri komanso zovuta zokhudzana ndi thanzi.
Gallic acid ndi antioxidant wamphamvu.Izi zikutanthauza kuti zimathandizira kuthana ndi kupsinjika kwa okosijeni, komwe kumatha kuwononga ma cell ndikuyambitsa matenda osiyanasiyana osatha (18, 19, 20).
Kafukufuku akuwonetsa kuti gallic acid's antioxidant katundu atha kukhala pansi pazabwino zake zomwe amati anticancer ndi zotsatira za neuroprotective, kutanthauza kuthekera kwake kuteteza kapangidwe kaubongo ndi magwiridwe antchito (11, 21, 22).
Kafukufuku wa labotale wasonyeza kuti ngakhale peel ya mango ili ndi antioxidant komanso anti-cancer properties, gallic acid yomwe ili nayo imakhala ndi anti-proliferative.Izi zikutanthauza kuti gallic acid ili ndi kuthekera kwapadera koletsa kukula ndi kufalikira kwa maselo a khansa (23).
Kafukufuku wina wa labotale adayika gallic acid pamwamba pa gamma-AlOOH nanoparticles, kapena tinthu tating'ono ta aluminium tokhala ndi antioxidant.Izi zidapezeka kuti zikuwonjezera mphamvu ya antioxidant ya nanoparticles (24).
Kafukufuku wina akuwonetsa kuti gallic acid ingalepheretse kuchepa kwa ubongo mwa kuchepetsa kutupa ndi kuwonongeka kwa okosijeni.Zingathandizenso kupewa sitiroko (25, 26).
Kafukufuku wina wa nyama akuwonetsa kuti gallic acid ikhoza kukhala ndi chitetezo pamakumbukiro pambuyo povulala koopsa muubongo.Izi zitha kukhala chifukwa cha antioxidant komanso anti-yotupa (27).
Zotsatira za neuroprotective za gallic acid zawonedwanso m'maphunziro a nyama.Kafukufukuyu adawona zinthu zina zomwe zimaganiziridwa kuti zimalepheretsa kusokonezeka kwaubongo mwa anthu omwe ali ndi matenda ashuga (28).
Ngakhale zotsatira zabwinozi, kafukufuku wambiri wa anthu akufunika kuti amvetsetse momwe gallic acid's antioxidant katundu angapindulire thanzi la munthu.
Kafukufuku akuwonetsa kuti gallic acid ili ndi antioxidant yamphamvu, antibacterial properties komanso imathandizira kulimbana ndi kunenepa kwambiri.Komabe, kafukufuku wambiri amachitidwa m'machubu oyesera ndi nyama, kotero maphunziro aumunthu amafunika.
Gallic acid imadyedwa bwino kuchokera ku zakudya zachilengedwe, makamaka chifukwa chosowa zovomerezeka komanso zophunzitsidwa bwino pamsika.
Komabe, kafukufuku wina wachikale wa nyama adapeza kuti oral gallic acid ndi yopanda poizoni pamlingo wofikira magalamu 2.3 pa paundi ya kulemera kwa thupi (5 magalamu pa kilogalamu) (29).
Kafukufuku wina wa zinyama adapeza kuti gallic acid yomwe imaperekedwa kwa mbewa pa mlingo wa 0.4 mg pa paundi ya kulemera kwa thupi (0.9 g pa kilogalamu) tsiku lililonse kwa masiku 28 sanasonyeze umboni wa poizoni mu mbewa (30).
Choyipa chachikulu cha gallic acid ndi kusowa kwa maphunziro a anthu komanso kusowa kwa zowonjezera zomwe zili ndi malingaliro ophunzitsidwa bwino komanso ochirikizidwa ndi kafukufuku.
Gallic acid ndi phenolic acid yomwe imapezeka muzomera, makamaka zipatso, mtedza, vinyo ndi tiyi.Ili ndi antioxidant, antibacterial komanso anti-obesity properties.
Chifukwa cha momwe zimapangidwira, zitha kukhala zopindulitsa makamaka ku matenda monga khansa ndi thanzi laubongo.Amagwiritsidwanso ntchito ngati chakudya chothandizira kupewa matenda obwera chifukwa cha zakudya.
Komabe, kafukufuku wambiri wa gallic acid wachitika m'machubu oyesera ndi nyama.Choncho, sizikudziwika ngati phindu lake limagwiranso ntchito kwa anthu.
Kuonjezera apo, ngakhale magwero ena akuwonetsa kuti gallic acid imapezeka ngati chowonjezera, zikuwoneka kuti imagulitsidwa makamaka chifukwa cha mankhwala.
Ngati muli ndi chidwi ndi ubwino wa gallic acid, yang'anani pa zakudya zachilengedwe mpaka kufufuza kwina kuchitidwa pa gallic acid supplements.
Yesani izi lero: Kuti muwonjezere gallic acid pazakudya zanu, ingowonjezerani mtedza ndi zipatso zosiyanasiyana pazakudya zanu zatsiku ndi tsiku.Mukhozanso kumwa kapu ya tiyi wobiriwira ndi kadzutsa.
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